Single Cell Dielectric Spectroscopy in a Micro-channel

نویسندگان

  • Y. Katsumoto
  • S. Omori
  • K. Sato
  • T. Umetsu
  • M. A. Brun
  • H. Soma
  • T. Hayakawa
  • S. M. Lee
  • K. Sakai
  • Y. Hayashi
  • A. Yasuda
  • M. Nagasawa
  • T. Morio
  • S. Mizutani
چکیده

We propose the idea of single cell dielectric spectroscopy for future clinical applications such as cell therapy and regenerative medicine. The structure of the microfluidic device is carefully designed to suppress the influence of electrode polarization on the dielectric spectra of single cells. Beads of uniform size distribution is used to determine the detection limit. As feasibility tests for biological samples, the dielectric spectra of single cells are measured for two kinds of cell lines and compared to those measured for the suspensions of the same cell lines.

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تاریخ انتشار 2011